产品货号:
Z13311
中文名称:
CENPB抗体
英文名称:
Anti-CENPB Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CENPB Antibody |
指标别名 | CENPB;Major centromere autoantigen B;Centromere protein B;CENP-B |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,ICC/IF,FCM |
基因名称 | CENPB |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence of human CENPB (HLEHDLVHVTRKNHA). |
实际分子量 | 80KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Centromere protein B also known as major centromere autoantigen B is an autoantigen protein of the cell nucleus.In humans,centromere protein B is encoded by the CENPB gene.This gene product is a highly conserved protein that facilitates centromere formation.It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family.It contains a helix-loop-helix DNA binding motif at the N-terminus,and a dimerization domain at the C-terminus.The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA.This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes.It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. |
Uniprot ID | P07199 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | centromere protein B |
蛋白名全称 | Major centromere autoantigen B |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells |
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